Suramin is not extensively metabolized and about 80% is eliminated via the kidneys. It was a remedy taken before flu season. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. It is used parenterally in the treatment of African trypanosomiasis and it has been used clinically with diethylcarbamazine to kill the adult Onchocerca. I do you a concern about the med beds and whether the DNA is actually being reconstructed our is it possible that our DNA is being changed-much the way the jab is changed and damaged. The Antidote to the Contagion. It can heal the intestinal lining in a way that other milks cannot, and then healing the leaky gut syndrome diminishes parts of autism. I believe people are so caught up in their own little bubble that they have no idea of what is going on in the real world. [10] Suramin uncommonly affects the eyes causing watery eyes, swelling around the eyes, photophobia, and changes or loss of vision. Raw Camel Milk can help reverse many parts of autism. "Antimicrobial activity of the essential oil of young pine shoots (Picea abies L.). This also can be made up into a tea. It has a sweet taste and I like it. The herb astragalus has been used for centuries as a Chinese and Indian medicine. Suramin contains six aromatic systems four benzene rings, sandwiched by a pair of naphthalene moieties plus four amide functional groups (in addition to the urea) and six sulfonic acid groups. Thank you! Suramin is manmade and is not a natural product found anywhere in Nature. We have two sons with Autism and are verbal but are not using full sentences accompanied by the usual jumping, head and hand movements and jumping. This is the most important Antidote. are there any meds that might be good alternatives to suramin? Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website. (2014). Thats my guess only. [24][25][26][27], 8,8'-{Carbonylbis[imino-3,1-phenylenecarbonylimino(4-methyl-3,1-phenylene)carbonylimino]}di(1,3,5-naphthalenetrisulfonic acid), O=C(Nc1cc(ccc1C)C(=O)Nc3c2c(cc(cc2c(cc3)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)c8cccc(NC(=O)Nc7cc(C(=O)Nc6cc(C(=O)Nc5c4c(cc(cc4c(cc5)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)ccc6C)ccc7)c8, InChI=1S/C51H40N6O23S6/c1-25-9-11-29(49(60)54-37-13-15-41(83(69,70)71)35-21-33(81(63,64)65)23-43(45(35)37)85(75,76)77)19-39(25)56-47(58)27-5-3-7-31(17-27)52-51(62)53-32-8-4-6-28(18-32)48(59)57-40-20-30(12-10-26(40)2)50(61)55-38-14-16-42(84(72,73)74)36-22-34(82(66,67)68)24-44(46(36)38)86(78,79)80/h3-24H,1-2H3,(H,54,60)(H,55,61)(H,56,58)(H,57,59)(H2,52,53,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80), The references used may be made clearer with a different or consistent style of, World Health Organization's List of Essential Medicines, Learn how and when to remove this template message, "Suramin Injection Advanced Patient Information", "Micromedex Detailed Drug Information for the Consumer: Suramin (Injection route)", "Our Formulary Infectious Diseases Laboratories CDC", "Trypanosomiasis, human African (sleeping sickness)", "CDC Infectious Diseases Laboratory: Our Formulary", "Suramin Injection Advanced Patient Information - Drugs.com", "Synthesis and StructureActivity Relationships of Suramin-Derived P2Y, "Inhibition of receptor/G protein coupling by suramin analogues", "International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy", "International union of pharmacology. [4] It is unclear if it is safe when breastfeeding. By accessing or using this website, you agree to abide by the Terms of Service, Full Disclaimer, Privacy Policy, Affiliate Disclosure, and Comment Policy. This is handy to know if you cannot source a suitable pine tree in your area. A lawn treated with Roundup would also have no grass, as well as no dandelions, no anything. Do we know the complete answer? It likes to be on the cold side of the mountain and doesnt do well on the warmer side. Of-course it helps towards keeping my website going. The study concluded that KSS may be beneficial for the treatment of ASD in females. The Eastern White Pine (. The information, including but not limited to, text, graphics, images and other material contained on this website are for informational purposes only. One important way that stress-triggered eATP is released occurs through pannexin 1 containing channels in the cell membrane. Use tab to navigate through the menu items. Naviaux Lab, 2023. Pure suramin is colorless when dissolved in water or saline as a 10% solution (100 mg/mL). [1][2] It is the treatment of choice for sleeping sickness without central nervous system involvement. It has recently been studied as a treatment for prostate cancer and is currently undergoing very promising studies as an effective treatment for Autism, ASD, and ADHD. This is the most important Antidote. Clinical trial evidence of suramin and autism. The synthesis of suramin was an extension of Paul Ehrlichs pioneering work that showed that certain chemical dyes were concentrated in microbial parasites like the trypanosomes that cause African sleeping sickness. PCAC: don't include. 6 (1992): 2166-2174. Medical Advice Disclaimer The information contained herein is not presented as medical advice nor should it be used as a substitute for consultation with a qualified health care practitioner. Eastern White Pine Tree Needles: A Natural Source of Anti-Infective Compounds, Suramin is strongly inhibitory to the replication of the coronavirus spike protein. We are doing this on a trial period to see if this interests our audience. PEA is a natural substance that's produced on demand in areas of local inflammation. Jacques Update:Facebook and social media platforms are cracking down on Conservative/holistic health content. (2014). 1 It is negatively charged at physiological pH and therefore binds to various intracellular targets including, but not limited to, ryanodine receptor 1 (IC 50 = 4.9 M), G protein-coupled receptors, P 2 purinergic receptors, PDGF, PKC, transferrin, DNA and RNA polymerases, sirtuins, and various . The most effective dosage solution is the Pine Needle Tincture. Pine trees, are everywhere! Rooibos Tea has become our all-time favourite tea now. Trypan blue is also known as diamine blue and Niagara blue. Exercise is a great (and natural) Adderall alternative. Weekly updates on the topics that matter the most to you! ", 19. 2. In addition, pharmaceutical grade suramin is hard to make. The approved pediatric drug suramin identified as a clinical candidate for the treatment of EV71 infection-suramin inhibits EV71 infection in vitro and in vivo. I love the way she says that they wouldnt be injecting people unless they already knew what could be done to reverse it. Im worried about the mark of the evil one. Suramin Inhibits SARS-CoV-2 Infection in Cell Culture by Interfering with Early Steps of the Replication Cycle. [9], It has been used in the treatment of river blindness (onchocerciasis). The drug is still sold by Bayer under the brand name Germanin. The claim: White pine tea contains suramin and shikimic acid, which can prevent COVID-19 vaccinated people from "shedding" the spike protein. I believe that most of the fake foods will be removed and people will learn how to eat food they were designed to eat. An alternative to synthetic drugs is the search for anti-parasitic plant extracts or secondary metabolites derived from them. Current status of the nomenclature and properties of P2X receptors and their subunits", "Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676", "Quality of life impact of three different doses of suramin in patients with metastatic hormone-refractory prostate carcinoma: results of Intergroup O159/Cancer and Leukemia Group B 9480", Scott LaFee and Heather Buschman. However, melarsoprol not only produces severe adverse reactions but also is extremely painful to administer. Our research is aimed at discovering a completely new way to think about the cause and treatment of autism and dozens of other complex chronic disorders. Suramin is just the first in a new class of drugs that will be synthesized to help regulate purinergic signaling. Ethanol was found to decrease the time-constant of deactivation of ATP-gated ion channels without affecting the time-constant of activation, indicating that ethanol inhibits the function of these receptors by an allosteric decrease in the affinity of the agonist binding site. (2017) conducted a trial that studied the impact of a single dose of suramin in children with autism and compared their result to a group of children who received the placebo drug (Saline). Suramin was shown to be safe and effective in three preclinical models of ASD9-11 and a small human clinical trial1 in peer-reviewed papers published between 2013-2017. Privacy Policy. Many of you have complained that you never see our content in your news feeds on social media. Suramin. It is not found in pine needles and cannot be found in any herbal teas. An analog of trypan blue, suramin, is used pharmacologically against trypanosomiasis. The first thing we noticed was the improvement in his articulation. 1 (1987): 143-148. According to credible, published research from scientists in Spain from La Quinta Columna, somebut not allinjections, appear to contain high levels of graphene oxide while some appear to be saline placebos. Suramin dosage IV: Dose is based on patient's body weight and response to the medication. Journal of clinical oncology 10, no. What a super easy way to give my body Suramin on a regular basis. Male Fern & Wormwood Sitz Bath Foods that Feed Parasites (MUST AVOID) 6 Natural Alternatives to Ivermectin with Herbs 1. Xu, H. Eric, Wanchao Yin, Xiaodong Luan, Zhihai Li, Leike Zhang, Ziwei Zhou, Minqi Gao et al. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. Weve tried everything else. New drugs to inhibit eATP release by regulating pannexin channels are being developed. Do you think that Rheum Palmatum is the richest plant? Journal of cellular biochemistry 29, no. How long would it take. The claims about suramin are made without evidence by a leading propagator of COVID and vaccine misinformation. Myers, Charles, Michael Cooper, Cy Stein, Renato LaRocca, M. M. Walther, Gary Weiss, Peter Choyke, Nancy Dawson, Seth Steinberg, and Margaret M. Uhrich. In summary, a lowered pHe enhanced the activity of all agonists at P2X2 receptors but, with the exception of suramin, not antagonists. Jaw dropping information on all food and the bodies response including learning difficulties. 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